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Coming soon: HD Therapeutics Conference 2012

An oasis of hope in the desert: the annual Huntington’s Disease Therapeutics Conference in Palm Springs, California, begins on 27th February. We’ll be bringing you live updates via Twitter and the web.

An exciting time

If 2011 is anything to go by, we predict that 2012 will be a big year for Huntington’s disease treatment research.

The new year has already brought exciting news of gene silencing success in primate trials and striking improvement in HD mice from injection of the ‘brain fat’ GM1.

Annual Therapeutics Conference

For the last 7 years the annual HD Therapeutics Conference in Palm Springs, California, has been a significant occasion for HD drug-hunters. It’s where the most exciting and cutting-edge treatment research is announced and discussed. It’s also a gathering of the world’s top HD researchers where ideas are shared and fruitful collaborations formed and nurtured.

The Conference begins very soon – Monday 27th February, to be exact. Your intrepid HDBuzz reporters Ed Wild and Jeff Carroll are going undercover at the Conference to bring you the latest news and buzz from the meeting.

The inside scoop from HDBuzz

Each day, we’ll be tweeting live updates from 9am to 6pm Pacific Time (that’s roughly 5pm to 2am in Europe). Follow @HDBuzzFeed on Twitter now, so you don’t miss anything.

If you prefer a daily digest, check HDBuzz.net or any of the HD sites that carry HDBuzz syndicated content. Each day’s news will be gathered together into a new article each evening, with our ever-popular ‘sunset conclusions’ to put things in context.

In the coming weeks, we’ll also bring you featured stories and interviews with some top scientists from the Conference.

Get in touch!

We want to hear from you, too, so send your questions, comments and queries to palmsprings@hdbuzz.net or tweet @HDBuzzFeed now or throughout the Conference.

So, get following, sign up for email updates and check the web frequently. Here’s looking forward to an inspiring Therapeutics Conference.

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Latest Research Articles

Treatment for neurological disorder could be repurposed for Huntington’s disease patients

Published date: 22 October, 2020

While developing a drug called branaplam for patients with SMA, the pharmaceutical company Novartis discovered that it could hold promise for people with HD. The FDA has granted a special status called Orphan Drug Designation to branaplam. An existing drug…for huntingtin lowering? The pharmaceutical company Novartis has announced that the U.S. Food and Drug Administration ... Read more Treatment for neurological disorder could be repurposed for Huntington’s disease patients

Updates from the EHDN Plenary Meeting 2020

Published date: 9 October, 2020

In September, the European Huntington’s Disease Network (EHDN) hosted a virtual webinar event which comprised presentations on some of the latest scientific research as well as clinical studies of Huntington’s disease (HD). Researchers, doctors, patients and other interested folks, tuned in for an afternoon of talks as well as question and answer sessions to learn ... Read more Updates from the EHDN Plenary Meeting 2020

Sad news from the SIGNAL study: pepinemab does not influence HD symptoms

Published date: 23 September, 2020

The SIGNAL clinical trial was designed to test a drug called pepinemab in people with early Huntington’s disease. The key results of that trial were recently announced, and unfortunately, pepinemab did not slow or improve HD symptoms as hoped. What was the SIGNAL trial, and who participated? The SIGNAL trial was launched in 2015 by ... Read more Sad news from the SIGNAL study: pepinemab does not influence HD symptoms

When genes are unstable: targeting somatic instability in HD

Published date: 8 September, 2020

What is somatic instability? We tend to think of DNA as a fixed blueprint, an overarching plan for the biological bricks and bridges that constitute our cells, organs, and bodies. But like any good plan, DNA is actually dynamic and adaptable. It gets frequent use as a template for creating the RNA messages that pave ... Read more When genes are unstable: targeting somatic instability in HD

Working as a team: Changes in brain development mean some brain regions may be slacking off

Published date: 17 August, 2020

The effect of the HD genetic expansion on brain development has been a hot topic in HD research. A team of researchers led by Dr. Sandrine Humbert at the Grenoble Institut Neurosciences, examined human fetal tissue to show that the mutant HD gene causes very early changes in the patterns of early brain development. But ... Read more Working as a team: Changes in brain development mean some brain regions may be slacking off

Caution urged for the use of gene-editing technology CRISPR

Published date: 12 August, 2020

A gene-editing tool known as CRISPR has been heralded as a breakthrough technology for scientists in the lab but also as a potential strategy to treat numerous genetic diseases, including Huntington’s. But a series of recent studies has suggested that CRISPR is less precise than previously thought, leading to unintended changes in the genome. Three ... Read more Caution urged for the use of gene-editing technology CRISPR

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